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Secondary endpoints: GSH concentrations in maternal and arterial and venous umbilical cord blood erythrocytes (by stratification based on treatment or degree of IPTB severity) and safety of antenatal NAC supplementation for mothers and infants Considering stratification for IPTB severity, median glutathione concentration in venous cord blood was similar in severe (median: 430 µmol/L) and moderate (median: 402 µmol/L) IPTB in the NAC arm ( P 1.0), whereas it was lower, however not significantly ( P 0.67), in severe (median: 391 µmol/L) than moderate (median: 522 µmol/L) IPTB group in the placebo arm (Supplemental Table S3)