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Larabee et al (2005) observed spotty, isolated hepatic cell death in male rats following short-term dermal exposure to JP-8, and the National Toxicology Program (1986) reported increased hepatic karyomegaly and liver amyloid in male and female mice following chronic (13 weeks for hepatic karyomegaly and 90 to 103 weeks for liver amyloid) dermal JP-5 exposure