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Trans-3-hexenoic acid-modified full-length GHRH(1-44) analogue — is a synthetic 44-amino acid stabilised growth hormone releasing hormone analogue and one of the most extensively characterised and clinically validated full-length GHRH receptor agonist research compounds available to laboratories in Ireland , a trans-3-hexenoic acid conjugated GHRH(1-44) peptide that activates the GHRH receptor with the complete pharmacophore geometry of full-length endogenous GHRH while the N-terminal trans-3-hexenoic acid modification confers resistance to dipeptidyl peptidase IV cleavage at the Tyr1-Ala2 dipeptide and extending circulating half-life relative to native GHRH(1-44) and enabling sustained episodic GH secretory stimulation from a full-length GHRH sequence