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Peptides as a drug class are sometimes described as having fewer off-target effects than small-molecule drugs because of their target specificity, and FDA guidance reflects this general principle
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[DOI] [PubMed] [Google Scholar] [65].Ji L, Jiang H, Bi Y, Li H, Tian J, Liu D, Zhao Y, Qiu W, Huang C, Chen L, Zhong S, Han J, Zhang Y, Lian Q, Yang P, Lv L, Gu J, Liu Z, Deng H, Wang Y, Li L, Pei L, Qian L, Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight, N