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Dihexa and Nle 1 -AngIV Induce Spinogenesis in Hippocampal Organotypic Cultures To further assess the physiologic significance of the spine induction witnessed in dissociated neonatal hippocampal neurons, the effects of dihexa and Nle 1 -AngIV on spine formation in organotypic hippocampal slice cultures were evaluated

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multi-peptide activity Gene expression research related to structural protein regulation Multi-pathway exploratory studies in regenerative biology, where combined peptide exposure is used to compare single- vs multi-peptide effects on matrix markers, cell motility, and gene-expression profiles in vitro