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In the 1990s, Professor Frank Ng and colleagues at Monash University in Melbourne, Australia, identified that the C-terminal fragment of HGH (residues 176 to 191) was responsible for the hormone's lipolytic activity, while the growth-promoting and insulin-antagonistic effects were mediated by different structural regions

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Anti-inflammatory and pain reduction effects are often the first changes patients notice, typically in the first one to two weeks