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This comprehensive modulation of energy balance represents a novel research strategy in the investigation of obesity, type 2 diabetes, and related metabolic disorders

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The once-daily subcutaneously administered GLP-1RA liraglutide (Victoza) was approved for the treatment of type 2 diabetes (in doses up to 1.8 mg) by the European Medicines Agency in 2009 and by the US Food and Drug Administration in 2010