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[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Schulz T.J., Zarse K., Voigt A., Urban N., Birringer M., Ristow M

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The involvement of AKR in drug resistance may be a consequence of AKR-catalysed metabolism of chemotherapeutic drugs/steroid hormones or because of the need to eliminate drug-induced cellular stress resulting from the generation of electrophiles or ROS